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The Beta Blocker and Clonidine Protocol


Lesson 5
Clonidine

5. Clonidine: Survival Curve

Wallace A.W., et. al., Effect of Clonidine on Cardiovascular Morbidity and Mortality after Non-Cardiac Surgery, Anesthesiology 101(2) 284-293, 2004

Clonidine Study Survival Curve

Here is the survival curve over 2 years demonstrating that patients treated for 4 days in the perioperative period had a reduced mortality. For those of you are disbelievers in the effect of BBAC on long term mortality Mangano et. al. 1996, Poldermans et. al. 2001, and Wallace et. al. 2004 all showed that BBAC effected two year mortality.

Does anybody want to be in the placebo group? We are looking for volunteers to be in the placebo group.


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